In a laboratory study, Comfortis started to kill fleas within 30 minutes and killed 100% of the fleas within 4 hours. Safety was shown in cats and kittens 14 weeks of age and older, in multiple laboratory studies and a field study in household cats. Call us at. Enter your pet to be our new Chief Barketing Officer, Give one 140 mg chewable tablet by mouth once a month. Cookie Notice Percentage of Dogs (%) with Adverse Reactions. Flexible ONCE A MONTH 208.113.197.86 Principal Display Panel - 1620 mg Blister Label, Comfortis (spinosad) Oral flea and tick preventatives for dogs are becoming more popular among veterinarians and dog lovers, but each dog and dog parent has unique needs or issues. Additional adverse reactions observed in studies were lethargy, decreased appetite, weight loss, and diarrhea. Puppies from dams treated at 1.3 times the maximum recommended therapeutic dose had lower body weights than puppies from control dams. Increased vomiting was observed at elevated doses, usually within 1 hour following administration. If you find a lower price including shipping on the identical product from a National Association of Boards of Pharmacy accreditted online pet pharmacy, we will honor that price at the time of order as long as the product is FDA/EPA approved for sale in the United States. Comfortis (spinosad) is a fast, safe and effective flea treatment for flea infestations on your dog or cat. Give Comfortis to your dog once a month. Bravecto: this flea and tick medicine is a topical ointment that goes between the felines shoulder blades. Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. In a separate well-controlled laboratory study, Comfortis demonstrated 100% effectiveness on the first day following treatment and >90% effectiveness on Day 30. Anyone have any luck using a legitimate website? CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). They told me that Comfortis is still out of stock everywhere, and that they were hoping to have it back in stock in March, but it has been held up again and they do not know when it will be available again. And the answer is; Yes! Comfortis can be given to dogs at least 14 weeks of age, weighing at least 5 lbs, and cats 14 weeks of age, weighing at least 4 lbs. sign up for exclusive sales and offers. 7 Different Types of Cat Litter Pros and Cons, Shoes for Dog Walkers: Best Shoes for Dog Walking. Comfortis is for use in dogs and puppies 14 weeks of age and older (see ANIMAL SAFETY). Puncture Here, Principal Display Panel - 560 mg Carton Label, Principal Display Panel 560 mg Box Label, Principal Display Panel - 810 mg Blister Label, Comfortis (spinosad) Your veterinarian should be made aware of all products that you administered and/or intend to administer to your dog. Reddit and its partners use cookies and similar technologies to provide you with a better experience. FREE Standard ShippingWhen You Spend $49+, 15% OFF FOR NEW CUSTOMERSUse code NC15 in cart (Excludes Merck), 2% Back on all PurchasesWith PetMeds Shop & Earn Rewards. To help you remember the monthly dosing schedule, stick-on labels are included for your calendar. The selective toxicity of spinosad between insects and vertebrates may be conferred by the differential sensitivity of the insect versus vertebrate nAChRs. Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Comfortis chewable tablets are beef flavored. 40.1-60 lb 810 mg If vomiting occurs within 1 hour of administration, redose the pet with another tablet. Comfortis is available in six tablet sizes for use in dogs: 90, 140, 270, 560, 810 or 1620 mg. Each tablet size is available in color-coded packages of 6 tablets. Prolonged spinosad-induced hyperexcitation results in prostration, paralysis, and flea death. 3.3-4.9 lb dogs and 2-4 lb cats These eggs hatch within a week; larvae then emerge and spin cocoons to become pupae. Dosage and Administration: Comfortis is given orally once a month, at the recommended minimum dosage of 13.5 mg/lb (30 mg/kg). In a well-controlled laboratory study, Comfortis began to kill fleas 30 minutes after administration and demonstrated 100% effectiveness within 4 hours. The adverse reactions are listed in decreasing order of frequency: vomiting, depression/lethargy, anorexia, ataxia, diarrhea, pruritus, trembling, hypersalivation and seizures. The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. KILLS FLEAS Comfortis has been demonstrated to be safe in cats when used according to label directions. Comfortis kills fleas before they can lay eggs when used monthly according to the label directions. Edit Jan 2023: its finally back in stock at chewy! If you have questions regarding the use of this product, consult your veterinarian, your cat's healthcare expert. For Dogs, Puppies, Cats and Kittens Is it safe to give my breeding dogs Comfortis? [Answer + Alternatives], Vitamin E Oil for Dogs: Dosage for Skin, Warts & Dry Nose. There are several alternatives to Comfortis flea treatment which many spoke about in the reddit thread, some of which treat more than just fleas. For most peoplethat's a lot of money! It is the most popular prescription flea-only drug in the United States. In controlled laboratory experiments, Comfortis eradicated 100 percent of fleas on dogs in just four hours. FAST ACTING This post may contain affiliate links. Privacy Statement| Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. One dam from each treatment group experienced early pregnancy loss and one additional high dose dam aborted late term. Comfortis Chewable Tablets for Dogs and Cats Rx. What distinguishes this treatment from the rest is its ease of use one chewable protects against fleas and ticks for up to three months. Cloudflare Ray ID: 7c09fb910d5f387f This number represents the amount of PetMeds Points you will receive by purchasing this item. Tell your veterinarian if your dog or cat has a history of seizures (epilepsy). Store at 68-77F (20-25C). Comfortis kills fleas and is indicated for the prevention and treatment of flea infestations (Ctenocephalides felis), for one month, on cats and kittens 14 weeks of age and older and two pounds of body weight or greater. For dogs: The most common adverse reaction reported is vomiting. Traffic still remains more leisure-driven and the heavy limitations that are still stifling demand on international routes affect traffic flows . If you have any questions about this information, please consult your veterinarian. You can only get Comfortis from an approved vet office, although some may offer an online prescription. It was approved in August 2012 for use in cats, but word has been slow to get out. Additional information can be found at www.Comfortis.com. Thank you, we will notify you when this product is available. If you see fleas on your dog within a month after your dog receives Comfortis, it is most likely that these are new fleas that have very recently emerged from pupae and jumped onto the dog. "Speed of flea knockdown of spinosad compared to afoxolaner, and of spinosad through 28 days post-treatment in controlled laboratory studies." Look back at the greatest flea treatments for dogs that we liked in the past. Easter Sale Get 10% Discount On All Orders. Kills fleas before they can lay eggs I give my cat Comfortis every month. For dogs: The most common adverse reaction reported is vomiting. A pilot study without a control group was conducted to analyze milk from three lactating dogs treated with an experimental formulation of spinosad at 1.5 times the maximum recommended dose administered at day 28 of gestation and 24 hours prior to parturition. Comfortis is a FDA-approved flea medicine that kills fleas and prevents flea infestations on dogs and cats for a whole month. Store Comfortis at room temperature (68-77 F). The worst part of a flea infestation is not what you can seeit's what you can't. Privacy Policy. One of the best treatments against adult fleas for cats and dogs is an oral flea medication that contains nitenpyram and goes by the name Capstar. 14 weeks of age and older 60.1-120 lb 1620 mg (Give with a meal), Manufactured for Elanco Animal Health, The primary target of action of Comfortis in insects is an activation of nicotinic acetylcholine receptors (nAChRs). Spinosyn A and spinosyn D have the chemical compositions 2-[(6-deoxy-2,3,4 tri-O-methyl--L-mannopyranosyl)oxy]-13- [[5 (dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]- 9 ethyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16btetradecahydro- 14-methyl-1H-as-indaceno[3,2-d] oxacyclododecin-7,15-dione and 2-[(6-deoxy-2,3,4-tri-Omethyl- -L-mannopyranosyl)oxy] 13-[[5-(dimethylamino) tetrahydro-6-methyl-2H-pyran-2 yl]oxy]-9-ethyl-2,3,3a,5a,5b, 6,9,10,11,12,13,14,16a,16b tetradecahydro-4,14-dimethyl- 1H-as-indaceno[3,2 d]oxacyclododecin-7,15-dione, respectively. The price being matched must be a product dispensed by an accredited licensed pharmacy or veternarian in the United States. Lot# In some cases, dogs vomited after receiving Comfortis. In comparison to topical products or flea collars, there is less likelihood of residue coming into contact with humans and less chance of it being washed off during rain (if dog gets wet) or regular grooming. MAX PET SUPPLIES PTY LTD. ABN: 86 603 803 738. If vomiting occurs within one hour of administration, redose with another full dose. 8:578. This includes the prevention and treatment of parasites such as fleas that may cause conditions that include flea allergy dermatitis, anemia, and other flea-related problems. Comfortis is the first FDA-approved, chewable beef-flavored tablet (derived from pork protein and hydrolyzed soy) that kills fleas and prevents flea infestations on dogs and cats for a full month. Store at 20-25C (68 -77F), excursions permitted between 15 to 30C (59 to 86F). Generic name: spinosad tablets The most common side effect is vomiting, which is mild and transient in most dogs and cats. Other common side effects in cats include diarrhoea and loss of appetite. Short answer, no, no comparison at all. Principal Display Panel - 1620 mg Carton Label, Principal Display Panel 1620 mg Box Label.